Biology and Chemistry (extra weekend edition)

Antagonistic coevolution accelerates molecular evolution

Mutational Analysis of the Poly(ADP-Ribosyl)ation Sites of the Transcription Factor CTCF Provides an Insight into the Mechanism of Its Regulation by Poly(ADP-Ribosyl)ation

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

A tetrahedral entropy for water

Special Feature: Method of the Year

Protein folding stability and dynamics imaged in a living cell

The simplicity of completion time distributions for common complex biochemical processes